Just wondering what the experience is like for cis men who have experienced estrogen dominance…
I’ve read that there are accounts of side effects in men who take estrogen for prostate cancer and who experience depression.
There are also the famous cases of Alan Turing and David Reimer. Was hoping for more first hand accounts of what the cis male experience is like on estrogen.
Just wondering if anyone has experiences they’re willing to share. Thanks!


I did estrogen monotherapy for about 2 months earlier this year. Quite frankly, the only changes I noticed was an immediate and significant increase in nipple sensitivity+size, and a reduction of nighttime erections. Other than that I didn’t notice any of the early changes which I had been lead to expect within the first few weeks: no emotional differences, no reduction in skin oiliness, no changes in body temperature, etc.
For what it’s worth, I was taking 1.4ml/week of 40% estradiol enanthate without any antiandrogens, am in my early 20s and have a very low body mass.